There is growing evidence that OA is not simply a disease related to aging or mechan- ical stress of joints but rather a “metabolic disorder” in which various interrelated lipid, metabolic, and humoral mediators contribute to the initiation and progression of the disease process. Indeed, OA has been linked not only to obesity but also to other cardiovascular risk factors, namely, diabetes, dyslipidemia, hypertension, and insulin resistance.
Osteoarthritis: Another Component of Metabolic Syndrome?
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Sabra Way MNIMH
Editor in Chief and Founder, Galen's Watch